Lab-on-chip systems for integrated bioanalyses

Lab-on-chip systems for integrated bioanalyses

Biomolecular detection systems based on microfluidics are often called lab-on-chip systems. To fully benefit from the miniaturization resulting from microfluidics, one aims to develop 'from sample-to-answer' analytical systems, in which the input is a raw or minimally processed biological, food/feed or environmental sample and the output is a quantitative or qualitative assessment of one or mor...

Integrated Polymeric Light Emitter for Disposable Photonic Lab on Chip Systems

This work presents the monolithic integration of a fluorophore-doped hybrid xerogel polymeric light emitter and a multiple internal reflection configuration (MIR) optofluidic system in a photonic lab on a chip (PhLoC). Two different air mirrors at both sides of the emitter were implemented that improves light coupling into the MIR system. The MIR inner walls were bio-functionalized with a perox...

Lab-on-a-chip with integrated optical transducers.

Taking the next step from individual functional components to higher integrated devices, we present a feasibility study of a lab-on-a-chip system with five different components monolithically integrated on one substrate. These five components represent three main domains of microchip technology: optics, fluidics and electronics. In particular, this device includes an on-chip optically pumped li...

Polymer multilevel lab-on-chip systems for electrochemical sensing

CMOS Circuits and Systems for Lab‐on‐a‐Chip Applications

Complementary metal oxide semiconductor (CMOS) technology allows the functional integration of sensors, signal conditioning, processing circuits and development of fully electronic integrated lab‐on‐a‐chip. On the other hand, lab‐on‐a‐chip is a technology which changed the traditional way by which biological samples are inspected and tested in laboratories. A lab‐on‐a‐chip consists of four main...